Formulasi Fast Disintegrating Tablet Ekstrak Rimpang Kunyit (Curcuma domestica) dan Perasan Umbi Kentang (Solanum tuberosum L)

نویسندگان

چکیده

Fast Disintegrating Tablet (FDT) merupakan tablet yang dapat dipecah dalam waktu kurang dari 60 detik saat diletakkan di atas lidah dengan jumlah air minimal. Kunyit dan kentang digunakan untuk menurunkan kadar asam lambung bertujuan mengobati pasien penderita gastritis. Tujuan penelitian ini membuat formulasi FDT rimpang kunyit (Curcuma domestica) perasan umbi (Solanum tuberosum L) variasi konsentrasi sodium starch glycolate sebagai bahan penghancur yaitu formula I (2%), II (3%) III (4%). Penelitian dilakukan metode observasi laboratorium. dihasilkan diuji mutu fisik meliputi; keseragaman ukuran, bobot, kekerasan, keregasan, hancur. Hasil menunjukkan bahwa I, II,dan telah memenuhi persyaratan pengujian granul maupun tablet. Konsentrasi paling baik pada adalah 4% hancur rata-rata 27 detik.Fast is that can be broken down in less than seconds when placed on the tongue with minimal amounts of water. Turmeric and potatoes are used to reduce acid levels stomach, which aims treat patients The purpose this study was make formulations turmeric potato tuber juice varying concentrations as a disintegrant, namely research conducted using laboratory observation method. tablets produced were tested for their physical quality, including size uniformity, weight hardness, firmness, disintegration time. results showed II, met requirements granule testing. best disintegrant concentration Formula III, an average time seconds.

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ژورنال

عنوان ژورنال: Journal of Experimental and Clinical Pharmacy

سال: 2023

ISSN: ['2775-1368']

DOI: https://doi.org/10.52365/jecp.v3i2.483